Enni Markkanen
After graduating from veterinary school and completing a DVM-PhD in basic cancer research at the University
of Zurich, Switzerland, I undertook postdoctoral training at the University of Oxford, focusing on DNA repair mechanisms and synthetic lethality as a cancer therapeutic strategy. In 2015, I returned to the University of Zurich to establish my independent research group. Our research connects veterinary and human oncology through the development and application of high-resolution molecular profiling of patient samples, including tissue-defined multi-omics analysis of FFPE material, functional drug-response assays, and single-cell as well as spatial transcriptomics. By combining cross-species comparative approaches with state-ofthe-art technologies, we seek to elucidate conserved mechanisms of cancer and advance novel, clinically translatable therapeutic strategies for both veterinary and human patients.