Ongoing EU Clinical Trials

last updated: 15/02/2024

ESVONC attaches great importance to innovation and evidence-based medicine in the field of veterinary oncology. Therefore, we are happy to share with you with a monthly overview of ongoing canine oncology trials in Europe. We are convinced that knowledge of these trials will enhance collaboration between researchers and clinicians, thus increasing recruitment for clinical trials and treatment options for dogs.

Please find below a non-exhaustive listing of ongoing trials as gathered in the Oncowaf database. For more details about these trials, please visit https://oncowaf.be/en/ClinicalTrials.

If you have an ongoing clinical trial and would like to add it to the Oncowaf clinical trial database and this mailing, please contact contact@oncowaf.com.

This list is an intiative of dr. Laetitia Cicchelero (DVM, PhD, Cross-health coordinator @ Faculty of Veterinary Medicine, Ghent University). Laetitia is initiator and inspirer of ONCOWAF. ESVONC wishes to thank Laetitia for her efforts to create this useful overview.

This list is updated on a monthly basis. 

(green: new trial, orange: trial enters its last month of recruitment).

Country	Requested tumour types for clinical trial	Type of trial
Belgium	Head & Neck tumours	Fluorescence-guided surgery	Hilde de Rooster hilde.derooster@ugent.be   Nayra Valle  nayra.valle@ugent.be
	Osteosarcoma, chondrosarcoma, benign osteolytic lesions	Percutaneous cementoplasty	Stella Minnoye Stella.minnoye@anicura.be
	Transitional cell carcinoma - bladder	Characterisation of biomarkers and immune response to improve diagnosis, prognosis and treatment	Annick Hamaide Annick.Hamaide@uliege.be
France	Multicentric lymphoma	Use of diffusion MRI to assess the extent of multicentric lymphoma	onco.chuvac@vetagro-sup.fr
	All tumours managed by a metronomic chemotherapy protocol	Pharmacokinetic study of metronomic chemotherapy agents residues	onco.chuvac@vetagro-sup.fr
	Solid tumours	Immunotherapy	Oncovet Clinical Research, Laurène Van Overbeke lvanoverbeke@oncovet-clinical-research.com
	Glioma	Oral treatment	Oncovet Clinical Research, Laurène Van Overbeke lvanoverbeke@oncovet-clinical-research.com
	Compassionate protocol for dogs with metastatic, recurrent or resistant cancer	Intravenous monoclonal antibody treatment	Oncovet Clinical Research, Asma Hamitouche  ahamitouche@oncovet-clinical-research.com,   Karolina Ziomek  kziomek@oncovet-clinical-research.com
Italy	All tumour types	Aspartame for the prevention of chemotherapy-induced diarrhoea	Paola Valenti paola.valenti@anicura.it
Poland	Compassionate protocol for dogs with metastatic, recurrent or resistant cancer	Intravenous monoclonal antibody treatment	Oncovet Clinical Research, Asma Hamitouche  ahamitouche@oncovet-clinical-research.com,    Karolina Ziomek  kziomek@oncovet-clinical-research.com
Portugal	Compassionate protocol for dogs with metastatic, recurrent or resistant cancer	Intravenous monoclonal antibody treatment	Oncovet Clinical Research, Asma Hamitouche  ahamitouche@oncovet-clinical-research.com   Karolina Ziomek  kziomek@oncovet-clinical-research.com
	Hepatic neoplasia	Thermoablation by microwaves or radiofrequency	Joaquim Henriques joaquim.henriques@anicura.pt
	Chemodectoma	Microwave ablation	Joaquim Henriques joaquim.henriques@anicura.pt
Spain	Mammary carcinoma	Use of metronomic chlorambucil, firocoxib and/or their combination as adjuvant therapy	Pachi Clemente veterinario@lamerced.net
	All tumour types	Aspartame for the prevention of chemotherapy-induced diarrhoea	Juan Borrego juan.borrego@ivcevidensia.es
Sweden	Mammary carcinoma	Use of metronomic chlorambucil, firocoxib and/or their combination as adjuvant therapy	Annika Tranaeus-Rowe Specialistdjursjukhusetstromsholm @evidensia.se
Switzerland	Sinonasal tumours	Heterogenous dose treatment radiotherapy	Carla Bley onkologie@vetclinics.uzh.ch
	High-grade glioma	Chemoradiation for high-grade glioma	Carla Bley onkologie@vetclinics.uzh.ch
	Meningioma	Conventional vs. stereotactic radiation therapy	Carla Bley onkologie@vetclinics.uzh.ch
	Cutaneous mast cell tumours	Lymphography and lymphoscintigraphy for sentinel node mapping and resection	Mirja Nolff  mnolff@vetclinics.uzh.ch
	Oral tumours	Fluorescence-guided surgery	Mirja Nolff  mnolff@vetclinics.uzh.ch
	Peripheral nerve sheath tumour of the brachial or lumbar plexus	Fluorescence-guided surgery	Mirja Nolff  mnolff@vetclinics.uzh.ch
	Soft tissue sarcoma	Fluorescence-guided surgery	Mirja Nolff  mnolff@vetclinics.uzh.ch
The Netherlands	Metastatic or recurrent insulinoma	Prospective evaluation of palliative and adjuvant toceranib phosphate therapy	Floryne Buishand  fbuishand@rvc.ac.uk
	Brain tumours	Minimally invasive radiotherapy (injection of radioactive holmium spheres)	Bas Van  Nimwegen s.a.vanNimwegen@uu.nl
	Lymphoma	Efficacy of PEG-L-asparaginase treatment	https://bit.ly/3RdrKm2
	Pheochromocytoma	Study and sample collection of pheochromoctomas to allow development of therapy for inoperable tumours	https://bit.ly/3Zg2iyf
United Kingdom	Metastatic or recurrent insulinoma	Prospective evaluation of palliative and adjuvant toceranib phosphate therapy	Floryne Buishand  fbuishand@rvc.ac.uk
	Mammary carcinoma	Use of metronomic chlorambucil, firocoxib and/or their combination as adjuvant therapy	Gerry Polton enquiries@ndsr.co.uk
	All tumour types	Aspartame for the prevention of chemotherapy-induced diarrhoea	Aura Veterinary  hello@auravet.com    University of Edinburgh HFSAreception@ed.ac.uk

ESVONC does not endorse any of the clinical studies listed above, and expressly disclaims any responsibility or liability for any of the content related to these studies. The use of the ESVONC listing for the purpose of recruitment can, however, be acknowledged in the material and methods of these studies.